M. S. Christodoulou, Nikolas Fokialakis, Daniele Passarella, Aída Nelly García-Argáez, Ornella Maria Gia, Ingemar Pongratz, Lisa Dalla Via, Serkos A. Haroutounian. Synthesis and biological evaluation of novel tamoxifen analogues. Biorg.Med.Chem. In Press

F. Calogero, S. Borrelli, G. Speciale, M. S. Christodoulou, D. Cartelli, D. Ballinari, F. Sola ,  C. Albanese, A. Ciavolella, D. Passarella,  G. Cappelletti,  S. Pieraccini, M. Sironi. 9-Fluorenone-2-carboxylic acid as scaffold for new tubulin interacting compounds. ChemPlusChem In Press

D. Cartelli, F. Casagrande, C. L. Busceti, D. Bucci, G. Molinaro, A. Traficante, D. Passarella, E. Giavini, G. Battaglia, G. Cappelletti. Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective. Scientific Reports  In Press

C. Peruzzotti, S. Borrelli, M. Ventura, R. Pantano, G. Fumagalli, M. S. Christodoulou, D. Monticelli, M. Luzzani, A. L. Fallacara, C. Tintori, M. Botta, D. Passarella. Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry. ACS Med. Chem. Lett.  2013, 4, 274-277.

E. Riva, M. Mattarella, S. Borrelli, M. S. Christodoulou, D. Cartelli, M. Main, S. Faulkner, D. Sykes, G. Cappelletti, J. S. Snaith, D. Passarella. Preparation of Fluorescent Tubulin Binders. ChemPlusChem 2013, 3, 222-226. Cover 2013, 3, 201.

M. S. Christodoulou , F. Zunino, V. Zuco, S. Borrelli, D. Comi, G. Fontana, M. Martinelli,  J. Lorens, L. Evensen, M. Sironi, S. Pieraccini, L. Dalla Via, O. M. Gia, D. Passarella. Camptothecin-7-yl-methanthiole: Semisynthesis and Biological Evaluation. ChemMedChem 2012, 7, 2134-2143.

A. Furlan, B. Roux, F. Lamballe, F. Conti, N. Issaly, F. Dalan, J-F. Gullemot, S. Richelme, M. Contersin, J. Bosch, D. Passarella, O. Piccolo, R. Dono , F. Maina. Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures. PLOSEone 7 (10) , art. no. e46738.

F. Colombo, C. Tintori, A. Furlan, S. Borrelli, M. S. Christodoulou, R. Dono, F. Maina, M. Botta, M. Amat, J. Bosch, D. Passarella. ‘Click’synthesis of a triazole-based inhibitor of Met functions in cancer cells. Biorg.Med.Chem. Lett. 2012, 22, 4693-4696.

A. Furlan, F. Colombo, A. Kover, N. Issaly, C. Tintori, L. Angeli, V. Leroux, S. Letard, M. Amat, Y. Asses, B. Maigret, P. Dubreuil, M. Botta, R. Dono, J. Bosch, O. Piccolo, D. Passarella, F. Maina. Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signalling. Eur.J.Med.Chem 2012, 47, 239-254.

R. Gaggeri, D. Rossi, M. S. Christodoulou, D. Passarella, F. Leoni, O. Azzolina, S. Collina. Chiral flavanones from Amygdalus lycioides Spach: structural elucidation and identification of  TNFalpha inhibitors by bioactivity-guided fractionation. Molecules 2012, 17, 1665-1674.

A. Furlan, F. Colombo, A. Kover, N. Issaly, C. Tintori, L. Angeli, V. Leroux, S. Letard, M. Amat, Y. Asses, B. Maigret, P. Dubreuil, M. Botta, R. Dono, J. Bosch, O. Piccolo, D. Passarella, F. Maina. Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signalling. Eur. J. Med. Chem. 2012, 47, 239-245.

F. Arioli, S. Borrelli, F. Colombo, F. Falchi, I. Filippi, E. Crespan, A. Naldini, G. Scalia, A. Silvani, G. Maga, F. Carraro, M. Botta, D. Passarella. N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the Synthesis of Inhibitors of Bcr-Abl. ChemMedChem 2011, 6, 2009-2018.

G. Cappelletti, D. Cartelli, B. Peretto, M. Ventura, M. Riccioli, F. Colombo, J. S. Snaith, S. Borrelli, D. Passarella. Tubulin-guided dynamic combinatorial library of thiocolchicine-podophyllotoxin conjugates. Tetrahedron 2011, 67, 7354-7357

E. Riva, A. Rencurosi, S. Gagliardi, D. Passarella, M. Martinelli. The Synthesis of (+)-Dumetorine and Congeners Using Flow Chemistry Technologies. Chemistry: a European Journal 2011, 17, 6221-6226.

M. Christodoulou, F. Colombo, D. Passarella, G. Ieronimo, V. Zuco, M. De Cesare, F. Zunino. Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors. Bioorg. Med. Chem. 2011, 15, 1649-1657.

E. Borsini, G. Broggini, F. Colombo, M. Khansaa, A. Fasana, S. Galli, D. Passarella, E. Riva, S. Riva. Enantiopure 2-piperidylacetaldehyde as useful building block in the diversity-oriented synthesis of polycyclic piperidine derivative. Tetrahedron: Asymmetry 2011, 22, 264-269.

S. Vitalini, A. Braca, D. Passarella, G. Fico. New flavonol glycosides from Aconitum burnatii Gáyer and Aconitum variegatum L. Fitoterapia 2010, 81, 940-947.

P. Magrone, F. Cavallo, W. Panzeri, D. Passarella, S. Riva. Exploiting enzymatic regioselectivity: A facile methodology for the synthesis of polyhydroxylated hybrid compounds. Org. Biom. Chemistry 2010, 8, 5583-5590.

E. Riva, D. Comi, S. Borrelli, F. Colombo, B. Danieli, J. Borlak, L. Evensen, J.B. Lorens, G. Fontana, O.M. Gia, L. Dallavia, D. Passarella. Synthesis and biological evaluation of new camptothecin derivatives obtained by modification of position 20. Bioorg. Med. Chem. 2010, 18, 8660-8668.

E. Riva, S. Gagliardi, M. Martinelli, D. Passarella, D. Vigo, A. Rencurosi. Reaction of Grignard reagents with carbonyl compounds under continuous flow conditions. Tetrahedron 2010, 17, 3242-3247.

D. Passarella, B. Peretto, R. Blasco, G. Cappelletti, D. Cartelli, C. Ronchi, J. Snaith, G. Fontana, B. Danieli, J. Borlak. Synthesis and Biological Evaluation of Novel Thiocolchicine-Podophyllotoxin Conjugates. Eur. J. Med. Chem. 2010, 45, 219-226.

D. Passarella, D. Comi, G. Cappelletti, D. Cartelli, J. Gertsch, A. R. Quesada, J. Borlak, K.-H. Altmann. Synthesis and biological evaluation of epothilone A dimeric compounds. Bioorg. Med. Chem. 2009, 17, 7435-7440.

D. Passarella, D. Comi, A. Vanossi, G. Paganini, F. Colombo, L. Ferrante, V. Zuco, B. Danieli, F. Zunino. Histone Deacetylase and Microtubules as Targets for the Synthesis of Releasable Conjugate Compounds. Bioorg. Med. Chem. Lett. 2009, 19, 6358-6363.

E. Riva, S. Gagliardi, C. Mazzoni, D. Passarella, A. Rencurosi, D. Vigo, M. Martinelli. Efficient Continuous Flow Synthesis of Hydroxamic Acids and Suberoylanilide Hydroxamic Acid Preparation. J. Org. Chem. 2009, 74, 3540-3543.

D. Passarella, G. Grieco, F. Cavallo, B. Checa, F. Arioli, E. Riva, B. Danieli. Enantiopure N-Boc piperidine-2-ethanol for the synthesis of (+)- and (-)-dumetorine, and (+)- and (-)-epidihydropinidine. Tetrahedron: Asymmetry 2009, 20, 192-197.